Showing posts with label DRUGS EDUCATION. Show all posts
Showing posts with label DRUGS EDUCATION. Show all posts

Thinking of going on Steroids? Read this first. By Vic Goyaram

Thinking of going on Steroids? Read this first
Researched and composed by Vic Goyaram
Exclusive for Bodybuilding Mauritius
We do not advocate steroid use
Bodybuilding Mauritius does not encourage the use of steroids and performance enhancing drugs. Every member who has been on our Facebook group since its inception can attest that we have never encouraged the use of steroids but rather preached the development of your natural potential by proper training, nutrition, supplementation and the necessary lifestyle modifications. Once you master the basics whatever else you do falls under your responsibility. Steroids do not make up for a lack of these aforementioned  bodybuilding "ingredients". Contrary to what may sometimes be said, steroids do not make up for a poor diet, lack of sleep and sloppy training. Neither are steroids the killer that the media portrays them to be but they are not without risks. Some people are more prone than others to experience the side effects of steroids while some can simply get away with it. 

The reason why I am writing this article is because through the Bodybuilding Mauritius group and my personal inbox we have obtained a number of queries regarding steroids from people who were not ready for this step.  In this article we present you some cases in which you must not go on steroids. 


No Steroid Case #1: Do not use steroids if you are still young.
Most of those interested in steroids are still very young. Some are still in their teens. At a young age steroids are not advised because your natural testosterone levels are still reasonably high although not as high as it would be if you were taking steroids. However, this can still allow you to make very solid gains naturally. In your teens and early-to-mid 20s your focus should be on building a natural foundation of muscle. I understand that at this age impatience is very common especially when one or two years of age difference can have a major impact on your natural growth. You see your friends are bigger than you, you see massive junior bodybuilders and you want to emulate them. I know that at this age you want to prove yourself, make a statement. I have been there too. Taking steroids at such a young age can mess up your endocrine system and this is definitely not worth it for a few pounds of extra muscle.

Young but not making decent progress
If you are not making the desired progress it is unlikely to be due to a lack of anabolic hormones in your system. The problem is more likely to be in your nutrition or training. You should get someone who is experienced to evaluate these for you. One more time, steroids won't make up for improper training or nutrition. 
If you are not making progress get a trainer to assess your training
and nutrition rather than jump on steroids
Bodybuilding is a marathon, not a sprint
Young people often want things to happen fast. Unfortunately, building muscle is not an overnight process. Building muscle takes time. This process may happen faster or slower in some people. Thus you may see you friends grow bigger and stronger at a faster rate than you. Bodybuilding itself is a long-term sport. You have all the time in the world to compete unless someone is pointing a gun at your head and forcing you to compete, which is very unlikely. You must devote your initial years as a teen bodybuilder to building a solid foundation of muscle rather than be in a hurry to go onstage and possibly considering steroids as an ally to help you achieve this. A guy of the age of 30 is considered young in bodybuilding, unlike most other sports. Just look at Toney "X-Man" Freeman who is still a top contender at the age of 48. Just look at Dexter Jackson who just won the Arnold Classic at the age of 42. 
Bodybuilding is a marathon, not a sprint. You can compete
at any age. Pursue health and longevity, not just massive muscles

(Pictured: Doug Brignole, NABBA Mr. Universe)
No Steroid Case#2: Adult with little training experience 
You must not use steroids if you are new to bodybuilding. You must bust your behind in the gym a good number of years naturally before even considering to go on steroids. You need to use your natural potential as much as possible by means of hard training and proper nutrition before considering to go on steroids. The latter should be the icing on the cake, the final piece of the puzzle as we say. You should not build your body on a foundation of steroids. Don't gear up too soon. 
Build a natural foundation before considering steroids
No Steroid Case #3: Diet is inadequate but want to do steroids
If you are not eating properly then it is very unlikely that your problem can be solved with steroids. Steroids won't make up for what's missing in your diet. Therefore, you can make good gains if you bring whatever is missing in your diet. You need to get someone experienced to analyse whether your diet is appropriate for your goals. You may think that you are eating a lot or sufficient macro-nutrients but on careful analysis there may be shortcomings. 

Let me take myself to illustrate an example. Currently I am able to afford only 150g of protein per day and 2000 calories total. In South Africa a 10ml vial of testosterone (250mg/ml) costs about the same price as 2kg of whey protein. What do you think I want to do? Buy the steroids or try to get the extra 50-75g of protein and 1500 calories that my body requires daily? I will go with the extra protein and 1500 calories because they themselves will "act like a steroid" once I bring these to my body. Meaning, they will give me good gains.  No matter how much I want to get really big and add more muscle, surprise people at how bigger I can get, out-lift everybody in the gym I know my aim cannot be achieved using testosterone when my body isn't getting enough nutrients. 
I must also wait before going on steroids
At the same time, once you decide to go on steroids don't only plan your cycle and post-cycle therapy (PCT). You need to plan your nutrition. You need to have a solid nutrition plan and know beforehand what you are going to eat and whether you will be on the money to ensure that your nutrition can be maintained. If your diet is off then doing a steroid cycle will be a mere waste of your money. The pain in the ass and delts from injections won't be worth it as well. 
Diet is key, on and off steroids
No steroid Case #4: Insufficient knowledge of steroids
Going on steroids is not about only popping a few pills or some weekly injections. I am not going to tell you how to do it but you must do your research beforehand.  A steroid cycle must be carefully planned rather than haphazard. You must know how long you will run the cycle, what your post-cycle therapy will be and what side effects you are likely to experience such that you have the proper remedial drugs handy. All these must be carefully planned. If you don't know about all these then please don't do steroids. Study more first. 

There are many good resources on steroids and your best bet would be publications like William Llewellyn's book titled "Anabolics". I am sure many of these books are available online and  you need to use these resources that back in the old days people didn't have. 
William Llewelyn's book is a good resource 
There are so many resources now but people get really lazy to dig into them for knowledge. There are many forums on the internet discussing steroids and you need to be really careful with these. Not everyone dispensing advice on steroids knows their stuff, some are knowledgeable while others are trying to push a certain steroid brand. Very likely on forums whenever you have a question concerning a cycle you need to be very specific and the members will expect you to have done your research first. Don't go and ask them "I want to take Deca. What do you advise?". You will be booed off the forum. You must be very specific in your question. Nobody will write you a cycle if you give the impression that you don't know the basics of your stuff or lazy to do your own prior research. Nobody will lay everything down for you unless maybe he is willing to date your sister. You must do your homework.
Steroid websites are numerous. Proceed with caution
You may also ask some of the big guys at your gym. Remember that not all big guys who juice are knowledgeable. You get some who are really dumb and who can write you a cycle that can kill your balls. Approach someone who seems to know his stuff very well and don't forget to do your research first and give him the impression that you are serious in your business and not just a kid who wants to take shortcuts. Again now if some guy is writing you insane cycles like 1000mg testosterone per week for your first cycle then drop him. Back off. 

No Steroid Case #5: Someone trying to sell you your first cycle without any advice
Given the massive demand for steroids, the latter is a lucrative business which has attracted not only bodybuilders but also dealers who previously had nothing to do with bodybuilding.  Most of these people may have little knowledge of bodybuilding and thus will not be in any position to give you advice about steroids. The same applies to dealers who are familiar to the bodybuilding world who may not have the time to attend to your questions because their main aim is record sales in record times. If someone sells you something without explaining to you how to use it, how to stack it and who doesn't even care whether or not you are ready then ditch that person. Do not buy his stuff. He is trying to make money off you. If you are, however, knowledgeable and know what you want then you are free to buy from who you want as long as you know his gear is legit. 
Not all dealers sell legit stuff. Most want only your money
No Steroid case #6: Peer Pressure and wanting to do like others
Learn to say NO if someone offers you steroids
Just because your friends or your training partner are using steroids doesn't mean that you  should use them too. Do not succumb to the need to do like others just to be accepted or for any other reason. Look deep into yourself and ask yourself what your aim is in bodybuilding. Is it to better yourself or to compete against others? Do your finances allow you to do like others? If your friends are taking steroids and eating 1kg of meat one day are you able to do the same if you take steroids like them? I personally don't care if I may be the only quite serious natural bodybuilder in my gym because I take massive pride in being one. I don't feel the need to do like others and do my first cycle although steroids are readily available to me. I will do so only when I am ready for that step in terms of both my bodybuilding goals and bank balance. Most of my bodybuilding friends are on steroids but they are also on 6-8 meals a day and are a dedicated and educated bunch. Neither my natural status nor their non-natural status change anything at the level of respect we have for each other. Think well whether you really need steroids. Sit down and reassess things. 

No Steroid Case #7: Steroids for the wrong reasons
Deca durabolin is not for joints and Anavar is not for fat loss. Do not use Deca-Durabolin because you have joint problems. Deca helps with dry and painful joints but it doesn't mean that you should use Deca just because you have these problems. I am mentioning this because I have sometimes received questions from people with no prior experience in steroids who have been advised to take Deca for joint problems. It would be very silly to run steroids just for joint lubrication, in my opinion. Maybe if the guy was a regular user an advice to also run Deca in his cycle would be understandable. You don't tell a beginner who is experiencing joint problems to run Deca, period.
Leave the Anavar for those who are experienced.
Don't use it as a first resort fat burner. You must be nuts to do so.
 
Similarly, while there are reports of Anavar and Winstrol working as a fat burner this doesn't mean that you should run these for losing some fat if you have no prior experience in steroids. You will be better off fixing your diet and then enlist the help of some over-the-counter thermogenics before considering to run these steroids. In most cases if you only need to lose some fat you won't really need to run any steroid. If you are a fat beginner don't think steroids will get you lean and jacked. You should be able to cut without gear. Cutting steroid cycles are for those who already know their business and have nailed down on their nutrition/ training and want that extra edge.

No Steroid Case #8: You have mental issues

Steroids have potential psychological effects and can affect your mood and emotions. If you are naturally an unhappy or depressed person then you will feel good for some time on steroids but will crash when you come off the steroids. Furthermore, if you have a short fuse and get angry easily then steroids may make this worse. Therefore, please make sure before going that route. You don't want to end up like a maniac and lose friendships and relationships. Whether or not the media has blown the psychological effects of steroids out of proportion, steroids have been shown in numerous studies to have psychological effects. 
Think well before sticking your first needle
Get your info and basics right


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©,2013, Veeraj Goyaram, Bodybuilding Mauritius. Any reprinting in any type of media is prohibited.

Disclaimer:
The Content on this site is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. BODYBUILDING MAURITIUS is not a medical or healthcare provider and your use of this site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties.  Qualifications of author of article: Bachelor of Science (Honours) in Biology (Department of Biosciences, University of Mauritius) and Master of Science in Medicine by research in Exercise Molecular Biology (Research Unit for Exercise Science and Sports Medicine, University of Cape Town). Correspondence: vicgoyaram@gmail.com
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Clenbuterol as a fat loss agent. By Vic Goyaram

Clenbuterol as a fat loss agent
 Researched and composed by Vic Goyaram

Clenbuterol: the new wonder 'mainstream' weight-loss drug
Clenbuterol (henceforth, Clen, for short) very often features in the fat burner arsenal of experienced competitive bodybuilders who probably have a decent understanding of the effects and side effects of the drug. However, I have recently been alarmed at the number of questions about Clenbuterol that I have received from a number of people who are most likely unaware of the basics of fat loss dieting and who have probably been told by their peers in the gym to use pop some Clen tabs to get ripped. In the pharmacies where I work part-time I often get women who come looking for Clen and Anavar for fat loss. 

This article is intended to give you a background on Clen, its effects and side effects in order to help you make an informed decision.  I have personally never used Clen and most of my experience comes from my understanding of biochemistry, pharmacology, physiology and my interaction with people who have used it for its physique enhancement effects.

The regulatory status of Clenbuterol

"Clen is not approved for human use in the US"
In the USA, Clen is not approved for human use even for medical purposes. It is only approved for use in horses suffering from respiratory problems. Clen is not intended for human use or for use in food producing animals in the USA. Outside the U.S., Clen is available on prescription for the treatment of breathing disorders like bronchial asthma in humans. Livestock producers in countries like Mexico and China use Clen in animals to improve meat quality. Clen is available in tablets (0.01 or 0.02 mg per tablet) and liquid preparations as Clenbuterol hydrochloride. 
In the US Clen is allowed only as a veterinary drug 

"Clen is listed as a banned substance by the WADA and natural bodybuilding federations"
Clen is listed by the World Anti-doping Agency (WADA) as a performance enhancing drug. Some natural bodybuilding federations like the International Natural Bodybuilding Association (INBA) list β-2 agonists like Clenbuterol and Salbutamol on their banned substances list as they follow the WADA protocol. 


Basic pharmacology of Clenbuterol
The chemical structure of Clenbuterol
Clen is a classified as a sympathomimetic drug. It is so named because it stimulates the sympathetic nervous system whose general action is to initiate a "flight or fight" response (an overall stimulant effect). Clen does this by activating receptors called β-2 adrenergic receptors. Stimulation of these β-2 adrenergic receptors gives rise to effects like:


  • Smooth muscle relaxation in the bronchi (bronchodilation). The main pharmacological use of Clen, asthma treatment, is in fact based on this effect.
  • Fat breakdown in adipose tissue (triglycerides broken down into fatty acids that can be oxidised) hence it's effect as a cutting drug.
  • Dilation of arteries that lead to skeletal muscle, allowing more efficient oxygen transportation to muscles.
  • Stimulation of anabolism in muscle (relevance of this effect in humans will be discussed below).
After ingestion, Clen is readily absorbed (70-80%) and remains in the body for awhile (25-39 hours). As a result of its long half life, the adverse effects of Clen (more below) are often prolonged.

Clen use in bodybuilding

A. Thermogenic and stimulant effects
Clen is used at about 60-120µg per day by bodybuilders often in combination with other fat burner drugs like the thyroid boosting drug T3, Yohimbine and Ephedrine/ Caffeine/ Aspirin (ECA) stack. The dosage is split in several intakes of 20µg. First time users generally test their sensitivity to Clen for determining the dosage. Clen is a fast acting drug and results come very fast, nearly immediately. An increase in body temperature is generally noted which is typical of Clen's well-known thermogenic effects.
Bodybuilders in contest preparation mode also stack Clen with steroids like Winstrol, Anavar and Equipoise. Users also report an increase strength with Clen especially in the first 2-3 weeks of use. This is possibly due to the stimulant properties of the drug. 

B. Receptor down-regulation
The body gets used to Clen fairly rapidly because the beta receptors are rapidly down-regulated. This means that the number of receptors decrease in response to the excess of beta-agonist (Clen), a usual response of the body. That is why Clen is generally used for relatively short periods of time, usually 4-6 weeks and use drugs like Ketotifen to try keep the receptors up and running.
When the body sees too much Clen (beta-agonist), it will decrease
the number of beta-receptors as a means of protecting itself
C. Anabolic effects
I would like to elaborate a lot on this one because a lot of people have asked me about the anabolic effects of Clen because they have read about it and thus want to use Clen to avoid the side effects (including injection pain) of steroids. Stimulation of the beta-2 receptors activates anabolic pathways in skeletal muscle and is the mechanism by which Clen exerts its anabolic effects.  Besides its effects on fat loss Clen may also produce a mild anabolic effect. I know you must be thinking "Hell yeah, I found what I wanted! Losing fat while putting on a bit of muscle!". Please be warned that while the mechanism of beta-2 agonist  anabolism is well established these effects may not happen with the doses used in humans. Let me tell you why:

The anabolic effect of Clen has been found in animals and not in humans. In these studies large amounts of Clen were used which is far in excess of what is safe for human consumption and what is recommended for bronchodilation. In a study by Choo and colleagues (1992), an anabolic effect was seen in rats that were given 4mg of Clen per kg of bodyweight. This means 400mg Clen for a 100kg person. Now remember that common doses for fat burning is 60-120MICRO grams per day. Be careful not to extrapolate animal data to humans especially unsupervised drug usage. Some people I know have reported that they retain muscle very well on clen but then they were also using anabolics like Winstrol and Equipoise so they real anabolic contribution of Clen cannot be determined. 

Below are two good review articles on the topic of Clen use to increase muscle mass and both come to the agreement that knowledge of the effects of Clen on muscle come from animal (laboratory or slaughter stock) experiments and not human data and therefore cannot be extrapolated to humans. Experiments on the safety, efficacy and cardiovascular side-effects are needed.
(Spann and Winter, 1995)
(Prather et al., 1995)
















Side effects
Although the reported fat burning effects of Clenbuterol are fantastic it doesn't come without a share of serious side effects. These side effects can be classified as follows:


  • Psychological side effects: As Clen is a nervous system stimulant emotional side effects are known to occur with its use. Many people report severe nervousness, paranoia and anxiety. Tremors are also very common and this reduced one's ability to perform physical tasks like writing, typing and holding objects. Insomnia may also result from Clen use especially when you have built up your dose. People who already suffer from psychological disorders like depression and anxiety are most likely to be at greater risk to experience the psychological side effects of Clen. Should you fall under such category it is best to speak to your medical practitioner before taking Clen. Do not play with your mental health.
  • Short and long term cardiovascular side effects: Clen users report that cardiovascular side effects appear quite rapidly. These side effects include tachycardia (heart palpitations) and high blood pressure and the headaches that accompany these. In some users these side effects have been enough to get them to quit using Clen. In experiments using rats, the long term use of Clenbuterol has been to cause an infiltration of collagen fibres in the heart wall. Collagen stiffens the heart muscle and reduces its functionality. Most Clen use is unsupervised and its consequences in people with pre-existing heart conditions and hypertension are not to be taken lightly. Taking Clen under these conditions can be a tragedy waiting to happen.  There have been cases of sudden death with Clen use.
  • Cramps: Clen is known to cause some bad cramps because it depletes the amino acid taurine. Taurine supplements help against Clen-induced cramps.
"Jumping" on Clen

First of all, I do not recommend Clenbuterol as a fat burner is you haven't mastered the basics of dieting like sorting out your diet and exercise program. Do not think you can get away by popping Clen tabs on a poor diet.  Do not look shortcuts and rather educate yourself. Do not listen to the guy who is selling you Clenbuterol and telling you "just drink this" without even talking about a proper diet strategy with you and asking about your medical history. Clen isn't your typical fat burner sitting on the shelves in the supplement store. Clen is serious business. Most of the questions about Clen use that I have received are from people who are clueless about their own nutrition. Imagine my horror when they also told me that they are doing endless sit-ups with no results and cannot answer me about the approximate number of calories they consume. I hope this article has shed some light on this topic. For those who want to learn more about dieting basics I will recommend the following two articles. Please read them carefully to know how your eating should be like before considering the use of Clen. They are written by two of my role models, Doug Brignole and Dr. Layne Norton.


The Ultimate Cutting Diet – Devised By Pro Natural Bodybuilder Layne Norton


References

Choo J.J, Horan M.A ,Little R.A, and Rothwell N.J. Anabolic effects of Clenbuterol on skeletal muscle are mediated by beta 2-adrenoceptor activation. Am J Physiol Endocrinol Metab July 1, 1992 263:(1) E50-E56

Prather ID, Brown DE, North P, et al. Clenbuterol: a substitute for anabolic steroids? Med Sci Sports Exerc 1995 Aug; 27(8):1118-21

Spann C, Winter ME.Effect of Clenbuterol on athletic performance. Ann Pharmacother. 1995 Jan; 29(1):75-7.

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©,2013, Veeraj Goyaram, Bodybuilding Mauritius. Any reprinting in any type of media is prohibited.

Disclaimer:
The Content on this site is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. BODYBUILDING MAURITIUS is not a medical or healthcare provider and your use of this site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties.  Qualifications of author of article: Bachelor of Science (Honours) in Biology (Department of Biosciences, University of Mauritius) and Master of Science in Medicine by research in Exercise Molecular Biology (Research Unit for Exercise Science and Sports Medicine, University of Cape Town). Correspondence: vicgoyaram@gmail.com
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